Health topic · Neurology

Amyotrophic Lateral Sclerosis

MedlinePlus, National Library of Medicine · Retrieved 2026-10-13

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles - the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice: • Trouble walking or running • Trouble writing • Speech problems Eventually, you lose your strength and cannot move. When muscles…

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Reference details

MedlinePlus topic groups
Brain and Nerves
Also called
ALS; Lou Gehrig's disease
MeSH terms
Amyotrophic Lateral Sclerosis
XML release date
10/13/2026 02:30:36

Overview

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles - the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice: • Trouble walking or running • Trouble writing • Speech problems Eventually, you lose your strength and cannot move. When muscles in your chest fail, you cannot breathe. A breathing machine can help, but most people with ALS die from respiratory failure. The disease usually strikes between age 40 and 60. More men than women get it. No one knows what causes ALS. It can run in families, but usually it strikes at random. There is no cure. Medicines can relieve symptoms and, sometimes, prolong survival. NIH: National Institute of Neurological Disorders and Stroke

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Retrieved: 2026-10-13. Text has been organized for reading; this import has not been independently reviewed by a clinician. It is not individualized medical advice.
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