Genetics reference · Ophthalmology

Meesmann corneal dystrophy

MedlinePlus Genetics, National Library of Medicine · Retrieved 2026-10-13

Meesmann corneal dystrophy is an eye disease that affects the cornea, which is the clear front covering of the eye. This condition is characterized by the formation of tiny round cysts in the outermost layer of the cornea, called the corneal epithelium. This part of the cornea acts as a barrier to help prevent foreign materials, such as dust and bacteria, from entering the eye. In people with Meesmann corneal dystrophy, cysts can appear as early as the first year of life.…

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Reference details

Inheritance patterns
Autosomal dominant
Other names
Corneal dystrophy, juvenile epithelial of Meesmann; Corneal dystrophy, Meesmann epithelial; Juvenile hereditary epithelial dystrophy; MECD; Meesman's corneal dystrophy; Meesmann corneal epithelial dystrophy; Meesmann epithelial corneal dystrophy
NLM review date
2012-08
NLM publication date
2020-08-18

Description

Meesmann corneal dystrophy is an eye disease that affects the cornea, which is the clear front covering of the eye. This condition is characterized by the formation of tiny round cysts in the outermost layer of the cornea, called the corneal epithelium. This part of the cornea acts as a barrier to help prevent foreign materials, such as dust and bacteria, from entering the eye. In people with Meesmann corneal dystrophy, cysts can appear as early as the first year of life. They usually affect both eyes and increase in number over time. The cysts usually do not cause any symptoms until late adolescence or adulthood, when they start to break open (rupture) on the surface of the cornea and cause irritation. The resulting symptoms typically include increased sensitivity to light (photophobia), twitching of the eyelids (blepharospasm), increased tear production, the sensation of having a foreign object in the eye, and an inability to tolerate wearing contact lenses. Some affected individuals also have temporary episodes of blurred vision.

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Source date: 2012-08. Retrieved: 2026-10-13. Text has been organized for reading; this import has not been independently reviewed by a clinician. It is not individualized medical advice.
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