Genetics reference · Cardiology

Catecholaminergic polymorphic ventricular tachycardia

MedlinePlus Genetics, National Library of Medicine · Retrieved 2026-10-13

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition characterized by an abnormal heart rhythm (arrhythmia). As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast heartbeat called ventricular tachycardia. Episodes of ventricular tachycardia can cause light-headedness, dizziness, and fainting (syncope). In people with CPVT, these episodes typically begin in childhood. If CPVT is not…

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Reference details

Inheritance patterns
Autosomal dominant; Autosomal recessive
Other names
Bidirectional tachycardia induced by catecholamines; Catecholamine-induced polymorphic ventricular tachycardia; CPVT; Familial polymorphic ventricular tachycardia; FPVT
NLM review date
2020-07
NLM publication date
2020-08-18

Description

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition characterized by an abnormal heart rhythm (arrhythmia). As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast heartbeat called ventricular tachycardia. Episodes of ventricular tachycardia can cause light-headedness, dizziness, and fainting (syncope). In people with CPVT, these episodes typically begin in childhood. If CPVT is not recognized and treated, an episode of ventricular tachycardia may cause the heart to stop beating (cardiac arrest), leading to sudden death. Researchers suspect that CPVT may be a significant cause of sudden death in children and young adults without recognized heart abnormalities.

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Source date: 2020-07. Retrieved: 2026-10-13. Text has been organized for reading; this import has not been independently reviewed by a clinician. It is not individualized medical advice.
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