Genetics reference · Oncology

Bladder cancer

MedlinePlus Genetics, National Library of Medicine · Retrieved 2026-10-13

Bladder cancer is a disease in which certain cells in the bladder become abnormal and multiply uncontrollably to form a tumor. The bladder is a muscular organ in the lower abdomen that stores urine until it can be removed (excreted) from the body. Bladder cancer may cause blood in the urine, pain during urination, frequent urination, the feeling of needing to urinate without being able to, or lower back pain. Many of these signs and symptoms are nonspecific, which means…

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Reference details

Inheritance patterns
Not inherited; Autosomal dominant
Other names
Bladder carcinoma urinary; Bladder tumor; Cancer of the urinary bladder; Cancer, bladder; Cancer, urinary bladder; Malignant bladder neoplasm; Malignant bladder tumor; Neoplasm of the bladder; Neoplasm of the urinary bladder; Tumor of the urinary bladder; Urinary bladder carcinoma; Urinary bladder neoplasm
Related genes or chromosomes
9
NLM review date
2020-02
NLM publication date
2024-09-17

Description

Bladder cancer is a disease in which certain cells in the bladder become abnormal and multiply uncontrollably to form a tumor. The bladder is a muscular organ in the lower abdomen that stores urine until it can be removed (excreted) from the body. Bladder cancer may cause blood in the urine, pain during urination, frequent urination, the feeling of needing to urinate without being able to, or lower back pain. Many of these signs and symptoms are nonspecific, which means they may occur in multiple disorders. People who have one or more of these nonspecific health problems often do not have bladder cancer, but have another condition such as an infection. Bladder cancer develops when tumors form in the tissue that lines the bladder. There are several types of bladder cancer, categorized by the type of cell in the tissue that becomes cancerous. The most common type is transitional cell carcinoma (also known as urothelial carcinoma); others include squamous cell carcinoma and adenocarcinoma. If the tumor spreads (metastasizes) beyond the lining of the bladder into nearby tissues or organs, it is known as invasive bladder cancer.

Sources and reuse

Original source summary. Follow the source links for additional information.
Source date: 2020-02. Retrieved: 2026-10-13. Text has been organized for reading; this import has not been independently reviewed by a clinician. It is not individualized medical advice.
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