Drug reference

About Omeprazole

Omeprazole is classified as proton pump inhibitor. Brand names associated with this community include Prilosec.

The label displayed here is for Prilosec OTC. Other brands or formulations may have different approved uses, doses and safety information; their names are included for navigation, not to imply interchangeability.

Source retrieved 2026-10-02 · DailyMed publication Jul 31, 2026 · View current label on DailyMed

Uses described in the label

treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn; this drug may take 1 to 4 days for full effect

Dosage and administration — label text

for adults 18 years of age and older this product is to be used once a day (every 24 hours), every day for 14 days it may take 1 to 4 days for full effect; some people get complete relief of symptoms within 24 hours 14-Day Course of Treatment swallow 1 tablet with a glass of water before eating in the morning take every day for 14 days do not take more than 1 tablet a day do not use for more than 14 days unless directed by your doctor swallow whole. Do not chew, crush, or suck tablets. Repeated 14-Day Courses (if needed) you may repeat a 14-day course every 4 months do not take for more than 14 days or more often than every 4 months unless directed by a doctor children under 18 years of age: ask a doctor. Heartburn in children may sometimes be caused by a serious condition.

Warnings

Omeprazole delayed-release tablet 20 mg (equivalent to 20.6 mg omeprazole magnesium)

Overdose information

In case of overdose, get medical help or contact a Poison Control Center right away.

Storage and handling

read the directions and warnings before use keep the carton. It contains important information. store at 20 to 25°C (68 to 77°F) and protect from moisture

Active ingredient

acetyl tributyl citrate, colloidal silicon dioxide, corn starch, croscarmellose sodium, hydroxypropyl cellulose, hypromellose 2910, magnesium stearate, methacrylic acid copolymer type c, microcrystalline cellulose, polyethylene glycol 400, polyethylene glycol 3350, polyethylene glycol 8000, polyvinyl alcohol, red iron oxide, sucrose, talc, titanium dioxide, triethyl citrate

Purpose

Acid reducer

Ask a doctor before use

had heartburn over 3 months. This may be a sign of a more serious condition. frequent wheezing, particularly with heartburn unexplained weight loss nausea or vomiting stomach pain

Ask a doctor or pharmacist

taking a prescription drug. Acid reducers may interact with certain prescription drugs.

Official, manufacturer and product resources

DailyMed: Prilosec OTC — complete product labelStructured product labeling · label set 37291cab-e350-d8e3-e063-6294a90a9cb1 · version 2
FDA application ANDA206582Approval history and regulatory documents. Availability varies by application type.
Other labels and formulations on DailyMedSearch results may include combination products. Check the active ingredients and route.

Research literature

Research references are provided for context. A paper mentioning a drug does not establish that it is suitable for a particular patient.

Search PubMed · Explore ClinicalTrials.gov

Encyclopedia context

Omeprazole, sold under the brand names Prilosec and Losec among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. It can be taken by mouth or by injection into a vein. It is also available in the fixed-dose combination medication omeprazole/sodium bicarbonate as Zegerid and as Konvomep. Common side effects include nausea, vomiting, headaches, abdominal pain, and increased intestinal gas. Serious side effects may include Clostridioides difficile colitis, an increased risk of pneumonia, an increased risk of bone fractures, and the potential of masking stomach cancer. Whether it is safe for use in pregnancy is unclear. It works by blocking the release of stomach acid. Omeprazole was patented in 1978 and approved for medical use in 1988. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2023, it was the tenth most commonly prescribed medication in the United States, with more than 45 million prescriptions. It is also available without a prescription in the United States.

From Wikipedia: Omeprazole. Text reused under CC BY-SA 4.0; formatting adapted. Contributor history. Encyclopedia material is not prescribing guidance.

News and media coverage

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About this record

This reference combines structured label data, bibliographic references and attributed encyclopedia material. It has not been independently reviewed by a clinician. It is not an exhaustive collection of every source or a live safety-alert service.

DrugChat retrieves label text from openFDA or DailyMed and links to the original DailyMed record. Imported text may lose tables or formatting; always check the complete original label. A missing section means it was not supplied in this record, not that the risk does not exist.

Retrieved 2026-10-02. About openFDA drug labels. Editorial and source policy.

Omeprazole drug information