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OTC products · Product label record

Itch Stopping drug information

DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE
HyVee Inc · TOPICAL

Product NDC: 42507-622

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Source label information, not individualized medical advice. This record applies to the product and labeler shown below. Compare the exact formulation, strength and country with your package and the current source label.
Generic nameDIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE
Labeler / manufacturerHyVee Inc
RouteTOPICAL
Drug classDrug class not supplied in source label
Product NDC42507-622
Label effective date2026-08-31

Official product label reference

Itch Stopping — HyVee Inc

This page contains 13 source sections for DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE, topical route. Label set 53157137-b980-45d2-aa10-8c111c0ec2f4, version 3.

Retrieved 2026-10-02 · openFDA dataset updated 2026-10-02 · Check the current DailyMed label

Label records can cover multiple strengths or package sizes. A label listing does not by itself establish FDA approval or current market availability. Check the source and application history for this specific product.

Uses described in the label

Uses • temporarily relieves pain and itching associated with: • insect bites • minor burns • sunburn • minor skin irritations • minor cuts • scrapes • rashes due to poison ivy, poison oak and poison sumac • dries the oozing and weeping of poison ivy, poison oak and poison sumac

Purpose

Purpose Topical analgesic Skin protectant
Dosage and administration — label text
Directions • do not use more than directed • adults and children 2 years of age and older: apply to affected area no more than 3 to 4 times daily • children under 2 years of age: ask a doctor
Warnings
Warnings For external use only Do not use • on large areas of the body • with any other product containing diphenhydramine, even one taken by mouth Ask a doctor before use • on chicken pox • on measles When using this product • avoid contact with the eyes Stop use and ask a doctor if • condition worsens or does not improve within 7 days • symptoms persist for more than 7 days or clear up and occur again within a few days Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Active ingredient
Active ingredients Diphenhydramine hydrochloride 2% Zinc acetate 0.1%
Do not use
Do not use • on large areas of the body • with any other product containing diphenhydramine, even one taken by mouth
Ask a doctor before use
Ask a doctor before use • on chicken pox • on measles
While using this medicine
When using this product • avoid contact with the eyes
When to stop use and seek help
Stop use and ask a doctor if • condition worsens or does not improve within 7 days • symptoms persist for more than 7 days or clear up and occur again within a few days
Child safety
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Storage and handling
Other information • store at 20°-25°C (68°-77°F)
Inactive ingredient
Inactive ingredients cetyl alcohol, diazolidinyl urea, methylparaben, PEG-2 stearate, PEG-20 stearate, propylene glycol, propylparaben, purified water
Questions
Questions or comments? 1-800-289-8343

Official sources and product identifiers

Substances listed: DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE

RxNorm identifiers: 1087026

Package NDC codes

42507-622-28, 42507-622-64

Further research and background

These are external searches for related information. Research, encyclopedia and news articles have not been imported into this product record.

Coverage and corrections

The text is extracted from a US structured product label. Tables are represented as text where supplied; formatting and illustrations may be lost. A missing section does not mean a risk is absent. This reference has not been independently reviewed by a clinician and is not a live safety-alert service.

Source retrieved 2026-10-02. Read the source policy.