Drug reference

About Fexofenadine

Fexofenadine is classified as antihistamine. Brand names associated with this community include Allegra.

The label displayed here is for Childrens Allegra Hives. Other brands or formulations may have different approved uses, doses and safety information; their names are included for navigation, not to imply interchangeability.

Source retrieved 2026-10-02 · DailyMed publication May 06, 2026 · View current label on DailyMed

Uses described in the label

reduces hives and relieves itching due to hives (urticaria). This product will not prevent hives or an allergic skin reaction from occurring.

Dosage and administration — label text

■ shake well before using ■ use only with enclosed dosing cup adults and children 12 years of age and over take 10 mL every 12 hours; do not take more than 20 mL in 24 hours children 6 to under 12 years of age take 5 mL every 12 hours; do not take more than 10 mL in 24 hours children under 6 years of age ask a doctor adults 65 years of age and older ask a doctor consumers with kidney disease ask a doctor Note: mL= milliliters

Warnings

(in each 5 mL) Fexofenadine HCl 30 mg

Active ingredient

edetate disodium, flavor, poloxamer 407, potassium sorbate, propylene glycol, purified water, sodium phosphate dibasic heptahydrate, sodium phosphate monobasic monohydrate, sucrose, titanium dioxide, xanthan gum, xylitol

Purpose

Antihistamine

Child safety

In case of overdose, get medical help or contact a Poison Control Center right away.

While using this medicine

■ do not take more than directed ■ do not take at the same time as aluminum or magnesium antacids ■ do not take with fruit juices (see Directions)

Do not use

■ to prevent hives from any known cause such as: ■ foods ■ insect stings ■ medicines ■ latex or rubber gloves because this product will not stop hives from occurring. Avoiding the cause of your hives is the only way to prevent them. Hives can sometimes be serious. If you do not know the cause of your hives, see your doctor for a medical exam. Your doctor may be able to help you find a cause. ■ if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

■ kidney disease. Your doctor should determine if you need a different dose. ■ hives that are an unusual color, look bruised or blistered ■ hives that do not itch

Official, manufacturer and product resources

DailyMed: Childrens Allegra Hives — complete product labelStructured product labeling · label set ff50d9cd-d849-43e8-b32a-4dcde798d3eb · version 1
FDA application NDA201373Approval history and regulatory documents. Availability varies by application type.
Other labels and formulations on DailyMedSearch results may include combination products. Check the active ingredients and route.

Research literature

Research references are provided for context. A paper mentioning a drug does not establish that it is suitable for a particular patient.

<b>Formulation, evaluation and characterization of fexofenadine IR and paracetamol SR multiparticulate drug delivery system</b>.Pak J Pharm Sci · 2026
Tamoxifen Therapy Is Associated With Altered Intestinal P-Glycoprotein Activity In Vivo.J Clin Pharmacol · 2026
Fexofenadine Induces ROS-Dependent Mitochondrial Dysfunction and Suppresses PI3K/AKT and MAPK Signaling in Cervical and Lung Cancer Cells.Cancers (Basel) · 2026
Second-generation H1 antihistamines for the treatment of chronic urticaria: a network meta-analysis.Front Med (Lausanne) · 2026
Discovery of Potent Antimalarial Agents Targeting Plasmodium falciparum DNA Gyrase B by Integrating Computational and Experimental Approaches.Chem Biol Drug Des · 2026

Search PubMed · Explore ClinicalTrials.gov

Encyclopedia context

Fexofenadine, sold under the brand name Allegra among others, is an antihistamine medication used in the treatment of allergy symptoms such as allergic rhinitis and urticaria. Therapeutically, fexofenadine is a selective peripheral H1 blocker. It is classified as a second-generation antihistamine because it is less able to pass the blood–brain barrier and cause sedation, compared to first-generation antihistamines. It was patented in 1979 and came into medical use in 1996. Fexofenadine is a therapeutic alternative on the World Health Organization's List of Essential Medicines. The patent expired in 2005, allowing generic options to be made available. In the United States, fexofenadine has been offered over-the-counter since 2011. In 2023, it was the 219th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

From Wikipedia: Fexofenadine. Text reused under CC BY-SA 4.0; formatting adapted. Contributor history. Encyclopedia material is not prescribing guidance.

News and media coverage

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About this record

This reference combines structured label data, bibliographic references and attributed encyclopedia material. It has not been independently reviewed by a clinician. It is not an exhaustive collection of every source or a live safety-alert service.

DrugChat retrieves label text from openFDA or DailyMed and links to the original DailyMed record. Imported text may lose tables or formatting; always check the complete original label. A missing section means it was not supplied in this record, not that the risk does not exist.

Retrieved 2026-10-02. About openFDA drug labels. Editorial and source policy.

Fexofenadine drug information